Tofwerk S2 ICP-TOF-MS

Picture of the Tofwerk S2 ICP-TOF-MS coupled to an ESL Bioimage 266 nm Laser Ablation System in ISTB Room 1307.

20 µm histological section of a mouse brain imaged on a TofWerk S2 ICP-TOF-MS equipped with an ESL Bioimage 266 nm Laser ablation system. Green = Zn, Blue = Cu, and Red = Fe.

Elemental maps of a mouse kidney using LA-ICP-MS (Top) and XRF (Bottom). Scale bar: 2 mm horizontal, 0.4 mm vertical. Putatively, regions a, b, c, and d, correspond to cortex, medulla, pelvis, and vasculature. All RGB intensities were scaled between 5% to 99% elemental content.

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Tofwerk S2 ICP-TOF-MS

Description/Accessories
Protocols

The Tofwerk S2 ICP-TOF-MS is a time-of-flight inductively coupled plasma mass spectrometer that allows for the near-simultaneous detection of all m/z within ~ 13 µs that couples the source and interface hardware of a Thermo Scientific iCAP RQ to a TOFWERK TOF mass analyzer. The iCAP RQ hardware provides versatile sample introduction, robust ICP, simple access to cones and lenses and the Q-cell technology. The TOF adds simultaneous all-element detection, linear response and mass resolving power >1000, while maintaining QMS-equivalent sensitivity. With high-speed mass spectral acquisition and simultaneous analysis of all isotopes, the icpTOF is the ideal ICP-MS detector for multi-element single particle analysis or fast laser ablation imaging.

Accessories: Coupled to Elemental Scientific Lasers (ESL) Bioimage 266 for high throughput laser ablation ICP-TOF-MS analysis of tissues and cells

Accessories: Integrated with Elemental Scientific Inc. (ESI) Cytospray single-cell autosampler

Cost (per hour): $100 internal / $140 external academic / $240 industry per hour

Schedule